Insulin stimulates the translocation of protein kinase C in rat adipocytes
- 6 November 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 257 (2), 337-340
- https://doi.org/10.1016/0014-5793(89)81565-0
Abstract
Insulin-induced changes in protein kinase C were examined in cytosol and membrane fractions of rat adipocytes enzymatically after Mono Q column chromatography and by immunoblotting. During a 5–20 min period of insulin treatment, cytosolic protein kinase C decreased by approximately 50%, whereas membrane protein kinase C increased nearly 2-fold. These findings suggest that insulin stimulates the translocation of protein kinase C in rat adipocytes.Keywords
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