Transmission of hormonal stimulation by cell-to-cell communication
- 1 April 1978
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 272 (5653), 501-506
- https://doi.org/10.1038/272501a0
Abstract
Rat ovarian granulosa cells and mouse myocardial cells respond to cell-specific hormones by cyclic[c]AMP-dependent mechanisms. In coculture, these heterologous cells communicate by means of gap junctions. Exposure of the cocultures to a hormone specific for 1 cell type causes the heterologous cells to respond through a cell contact-dependent mechanism. These studies suggest that this cross-stimulation results from the intercellular communication of a mediator that is common to both cell types. The communicated mediator may be cAMP.This publication has 35 references indexed in Scilit:
- Size Limit of Molecules Permeating the Junctional Membrane ChannelsScience, 1977
- Junctional Permeability and Its ConsequencesPublished by Springer Nature ,1977
- Transfer of radioactive material between electrically coupled neurons of the leech central nervous systemBrain Research, 1975
- Metabolic Coupling, Ionic Coupling and Cell ContactsNature, 1972
- Junctions between Cancer Cells in Culture: Ultrastructure and PermeabilityScience, 1971
- Permeability and Structure of Junctional Membranes at an Electrotonic SynapseScience, 1969
- The diffusion of radiopotassium across intercalated disks of mammalian cardiac muscleThe Journal of Physiology, 1966
- Cell-to-Cell Passage of Large MoleculesNature, 1966
- PERMEABILITY OF MEMBRANE JUNCTIONS*Annals of the New York Academy of Sciences, 1966
- Transmission at the giant motor synapses of the crayfishThe Journal of Physiology, 1959