Cryptococcosis

Abstract
Cryptococcosis is the name given to an infection having local and/or systemic lesions caused by the yeast-like organism Cryptococcus neoformans, formerly known as Torula histolytica. It is not a common disease in man. An exhaustive and admirable review of this topic was presented recently by Littman and Zimmerman,1 who estimated that over 200 cases had been reported in the world literature up to 1956. The most commonly involved site in human cryptococcosis is the central nervous system. The lungs are second in frequency. Presenting symptoms most often express these predilections. Cutaneous cryptococcosis is unusual. In the most recent compilation2 a total of 37 cases was recorded, although isolated references to unpublished cases are found occasionally. Some confusion arises in consulting the literature because of the following factors. Classification of the Cryptococcus organism is not exact. Much is still to be learned concerning its