A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats
- 1 May 1998
- journal article
- Published by Wolters Kluwer Health in Pain
- Vol. 76 (1), 151-157
- https://doi.org/10.1016/s0304-3959(98)00037-2
Abstract
This study used streptozotocin (STZ; 50 mg/kg i.p.) diabetic rats and monitored weekly thermal and mechanical nociceptive thresholds for 8 weeks diabetes. Rats developed mechanical hyperalgesia as soon as 2 weeks after STZ injection. Thermal nociceptive threshold was not altered up to 8 weekKeywords
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