Lymphocyte transformation to denatured type i collagen and b lymphocyte alloantigens in rheumatoid arthritis
Open Access
- 1 April 1980
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 23 (4), 424-432
- https://doi.org/10.1002/art.1780230405
Abstract
Peripheral blood lymphocytes transformed significantly to denatured type I collagen in 22 of 38 patients with rheumatoid arthritis (58%), 1 of 9 patients with Reiter's disease (P < 0.05), and 9 of 32 controls (28%) (P < 0.01). Determination of HLA antigens revealed significant differences between 24 rheumatoid arthritis (RA) patients and a control population for HLA-DRw4 (75% versus 23%). No correlation was observed between lymphocyte transformation to collagen and antibodies to collagen, rheumatoid factor, stage or duration of RA, or HLA antigens.This publication has 35 references indexed in Scilit:
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