Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands
Open Access
- 1 August 2007
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 282 (35), 25677-25686
- https://doi.org/10.1074/jbc.m702311200
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Identification of the Molecular Mechanisms by Which the Diterpenoid Salvinorin A Binds to κ-Opioid ReceptorsBiochemistry, 2005
- Application of a Kinetic Model to the Apparently Complex Behavior of Negative and Positive Allosteric Modulators of Muscarinic Acetylcholine ReceptorsJournal of Pharmacology and Experimental Therapeutics, 2004
- International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative PharmacologyPharmacological Reviews, 2003
- Allosteric Site on Muscarinic Acetylcholine Receptors: Identification of Two Amino Acids in the Muscarinic M2Receptor That Account Entirely for the M2/M5Subtype Selectivities of Some Structurally Diverse Allosteric Ligands inN-Methylscopolamine-Occupied ReceptorsMolecular Pharmacology, 2003
- G Protein-Coupled Receptor Allosterism and ComplexingPharmacological Reviews, 2002
- Seven-transmembrane receptors: crystals clarifyTrends in Pharmacological Sciences, 2002
- Allosteric binding sites on cell-surface receptors: novel targets for drug discoveryNature Reviews Drug Discovery, 2002
- Crystal Structure of Rhodopsin: A G Protein-Coupled ReceptorScience, 2000
- Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled ReceptorsEndocrine Reviews, 2000
- SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modelingElectrophoresis, 1997