EQUATIONS FOR TRACER EXPERIMENTS
Open Access
- 1 November 1949
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 28 (6 Pt 1), 1297-1307
- https://doi.org/10.1172/jci102197
Abstract
A set of simple differential equations have been developed to describe the movement of isotopes across barriers in biological systems. These equations cover the following examples: (a) uptake of stable isotopes from a constant source as shown by the uptake of deuterium in maternal and fetal rat cholesterol; (b) uptake of K42 by red blood cells from dilute plasma soln.; (c) flow of Na out of the plasma in man; (d) uptake of Na from the plasma into the cerebrospinal fluid of man. There is a short discussion on the possibility of differentiating between ultra-filtration and secretion, and also on the criteria for precursors.This publication has 8 references indexed in Scilit:
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