CHEMOTHERAPY OF AVIAN MALARIA

Abstract

The review "is confined to the chemotherapeutic aspects of avian malaria: no attempt has been made to include other studies on avian malaria which have contributed to our knowledge of the disease." The topics covered are methods (birds, inoculation, drug administration, criteria for estimating drug activity), the therapeutic effect of quinine and other derivatives of cinchona bark, arsphen-amine, atoxyl, methylene blue, stovarsol, atabrine, plas-mochin, mercurochrome, and sulfanilamide derivatives; the action of drugs on different stages of the parasite; species and strain variation in susceptibility to drugs; the question of completeness of cures; drug-fastness; studies in vitro; and the mechanism of action of drugs.