PLASMA CREATININE CONCENTRATION AND CREATININE CLEARANCE IN CLINICAL WORK
- 1 October 1955
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 43 (4), 731-739
- https://doi.org/10.7326/0003-4819-43-4-731
Abstract
The authors sum up 8 years experiences with endogenous creatinine clearance and discuss methods for estimation of creatinine. Normal total "Jaffe-positive substances" in plasma almost never exceed 1.30 mg/ 100 ml. There is a close correlation between increased plasma value and decreased renal function. Determination of "endo-genous creatinine clearance" gives no more information than the plasma concentration alone, which can be seen from the fact that the product of the plasma creatinine concentration (in mg/ 100 ml) and the creatinine clearance (in ml/minute) is quite constant and rarely will be found very far from 100, i.e., the average normal creatinine clearance value.Keywords
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