ENDOCRINE CHANGES DUE TO AUDITORY STRESS

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Abstract
In a study of the changes of the endocranium due to auditory stress, female Wistar strain rats weighing 194 g were subjected to 1 min. or 5 min. auditory stimulation with a mean intensity of 110 db and at frequencies of 375-500 cps. All animals were sacrificed on the day following the last auditory treatment. Application of intense sound stimulation results in reduction of weight gain. Adrenal hyperplasia, partial inhibition of ovarian activity, reduction in weight and vascularity of the uterus and a loss in liver weight was noted. Although no changes in either pituitary or thyroid weight is induced by intense sound stimulation, significant changes in pituitary cell type and in thyroid colloid storage result. Appetite is affected in the sound-stressed animals and food consumption is significantly reduced.