Incorporation of Glycine Into Protein Fractions of Nuclei of Liver and Hepatoma.
- 1 October 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 96 (1), 21-24
- https://doi.org/10.3181/00379727-96-23384
Abstract
A procedure is described for the separation of the proteins of cell nuclei into several fractions which differ in solubilities and in glycine content. Twenty hours after intraperitoneal injection of glycine-1-C14 into adult rats bearing subcutaneously transplanted hepatomas, the specific activities of the protein fractions of the nuclei of liver and tumor were in the descending order: residual lipoprotein globulins > histone fraction III > histone fraction II. Each of the protein fractions of the nuclei of liver cells had higher specific activities than corresponding protein fractions of the hepatoma with the notable exception of the histones which were in the reverse relationship.Keywords
This publication has 7 references indexed in Scilit:
- Protein Synthesis in Isolated Cell NucleiNature, 1955
- The incorporation of 15N, 35S and 14C into nucleic acids and proteins of rat liverBiochimica et Biophysica Acta, 1953
- Protein components of chicken erythrocyte nucleiBiochimica et Biophysica Acta, 1953
- A lipoprotein of rat liver nucleiExperimental Cell Research, 1953
- UPTAKE OF GLYCINE-N15 BY COMPONENTS OF CELL NUCLEIThe Journal of general physiology, 1952
- CYTOCHEMICAL STUDIES .5. ON THE ISOLATION AND BIOCHEMICAL PROPERTIES OF LIVER CELL NUCLEI1952
- THE NUCLEIC ACIDS OF PLANT TISSUES .1. THE EXTRACTION AND ESTIMATION OF DESOXYPENTOSE NUCLEIC ACID AND PENTOSE NUCLEIC ACID1950