Ueber eine Familie mit multiplen Missbildungen an Handen und Fuessen

Abstract

Summary In a family 5 females belonging to 3 generations were found with following malformations: Syndactyly (webbed up to the nails), oligodactyly, tendency towards duplication of digits, and brachydactyly. The intrafamiliar variability was not considerable with exception of an probandus having with 5 digits (with duplication on one digit). On the base of ontogeny the question is discussed if the disturbing factor concerning the palm of hand or concerning the squeleton is prevalent. In this family the two dispositions are probably combined. In bibliography a pedrigree with this combination of multiple malformations was not found.