PRELIMINARY EVIDENCE FOR TRAPPING OF ANTIGEN-SPECIFIC LYMPHOCYTES IN LYMPHOID-TISSUE OF ANERGIC TUBERCULOSIS PATIENTS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 26 (1), 129-132
Abstract
Lymphocyte-transformation responses to mycobacterial antigens were studied, using paired blood and lymph node samples from normal Ugandans (hernia repairs or orthopedic cases), or from patients with tuberculosis, Mycobacterium ulcerans infection or injection abscesses. The results suggest that in some individuals, antigen reactive cells, although absent from the periphery, may be demonstrable in the lymph nodes. This phenomenon is most striking in skin-test negative tuberculosis patients.