Synthesis of 10-substituted 5H-pyrido[3′,4′ :4,5]pyrrolo[2,3-g]isoquinolines

Abstract
The preparation of 6-amino-5-methyl isoquinolin-1 (2H)-one is described. Starting from this key intermediate, several derivatives of 5H-pyrido[3′,4′ :4,5]pyrrolo[2,3-g]isoquinoline substituted with various alkyl amino-groups at their 10-position have been synthesized.

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