Targeted disruption of NDST‐1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice

Abstract
In order to address the biological function of GlcNAc N‐deacetylase/N‐sulfotransferase‐1 (NDST‐1), we disrupted the NDST‐1 gene by homologous recombination in mouse embryonic stem cells. The NDST‐1 n...