Inhibitors: resolving diagnostic and therapeutic dilemmas
- 16 May 2002
- journal article
- review article
- Published by Wiley in Haemophilia
- Vol. 8 (3), 280-287
- https://doi.org/10.1046/j.1365-2516.2002.00626.x
Abstract
The good quality of life now anticipated by individuals with haemophilia A and B can be drastically altered by the unpredictable development of an inhibitor, a polyclonal high‐affinity IgG antibody d...Keywords
This publication has 47 references indexed in Scilit:
- Lack of evidence for increased inhibitor incidence in patients switched from plasma‐derived to recombinant factor VIIIHaemophilia, 2001
- Structure of a factor VIII C2 domain–immunoglobulin G4κ Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIIIBlood, 2001
- The French haemophilia cohort: rationale and organization of a long-term national pharmacosurveillance systemHaemophilia, 2001
- Use of prothrombin complex concentrates and activated prothrombin complex concentrates as prophylactic therapy in haemophilia patients with inhibitorsHaemophilia, 1999
- The German National Immune Tolerance Registry, 1997 UpdateVox Sanguinis, 1999
- Immunoadsorption for removal of inhibitors: update on treatments in Malmö–Lund between 1980 and 1995Haemophilia, 1998
- Factor IX Inhibitors and Anaphylaxis in Hemophilia BJournal of Pediatric Hematology/Oncology, 1997
- Induction of Immune Tolerance in Patients with Hemophilia A and InhibitorsJournal of Pediatric Hematology/Oncology, 1992
- Induction of Immune Tolerance in Patients with Hemophilia and Antibodies to Factor VIII by Combined Treatment with Intravenous IgG, Cyclophosphamide, and Factor VIIINew England Journal of Medicine, 1988
- Immunosuppressive Treatment in Haemophiliacs with Inhibitors to Factor VIII and Factor IXScandinavian Journal of Haematology, 1976