Spontaneous nucleation of microtubules
- 1 May 1995
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review E
- Vol. 51 (5), 5058-5063
- https://doi.org/10.1103/physreve.51.5058
Abstract
The spontaneous nucleation of individual microtubules from tubulin dimers is observed directly under conditions of marginal nucleation. The results are compared with measurements of bulk turbidity following a deep quench [W. A. Voter and H. P. Erickson, J. Biol. Chem. 259, 10 430 (1984)]. The size of the critical microtubule nucleus is 12±2 tubulin dimers in the two regimes, but the assembly pathway is different.Keywords
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