CATALEPTIC SYMPTOMS FOLLOWING BILATERAL CORTICAL LESIONS IN CATS

Abstract

A peculiar syndrome in many ways suggestive of catalepsy was observed in cats following a one-stage operation in which the rostral regions of the cerebral neocortex were bilaterally removed. These animals were characterized by a cataleptic state in which there were to be observed sudden suspensions of voluntary motion, a lowered sensibility to painful and emotional stimuli, and a high degree of plasticity of the somatic musculature. Observations were made on both acute and chronic preparations. These animals could be made to assume abnormal postures for long periods of time by virtue of a high degree of plasticity of the musculature. Such plasticity was most pronounced during the first week or two following operation. A definite deficiency in the ability to initiate and maintain movements of the extremities such as, for example, might be employed in the act of walking was apparent in all of the animals throughout the survival periods. The general impression of stolidity characterized these animals. Their reactions to environmental situations were always rather negative. Many showed no visible response to painful stimulation.