Preparation and pharmacological properties of 4-hydroxymethyl-2-(3′-amino-4′-hydroxyphenyl)-1:3-dithia-2-arsacyclopentane (Mapharside-BAL compound)

Abstract

Mapharside-BAL compound (I) injected in rats is more toxic than mapharside (II). With one mol. excess BAL, I has 1/5 the toxicity of II. Repeated doses of BAL will save animals from the toxic effects of II. I is more toxic than II for Colpidium.