OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α
- 1 February 2005
- journal article
- Published by Elsevier in Molecular Cell
- Vol. 17 (4), 503-512
- https://doi.org/10.1016/j.molcel.2005.01.011
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Hypoxia Up-regulates Prolyl Hydroxylase ActivityJournal of Biological Chemistry, 2003
- HIF-1 as a target for drug developmentNature Reviews Drug Discovery, 2003
- HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 in normoxiaThe EMBO Journal, 2003
- Characterization of the Human Prolyl 4-Hydroxylases That Modify the Hypoxia-inducible FactorJournal of Biological Chemistry, 2003
- Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathwayProceedings of the National Academy of Sciences, 2002
- Role of Prolyl Hydroxylation in Oncogenically Stabilized Hypoxia-inducible Factor-1αJournal of Biological Chemistry, 2002
- YOS9, the Putative Yeast Homolog of a Gene Amplified in Osteosarcomas, Is Involved in the Endoplasmic Reticulum (ER)-Golgi Transport of GPI-anchored ProteinsJournal of Biological Chemistry, 2002
- Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural FamilyJournal of Biological Chemistry, 2002
- A Conserved Family of Prolyl-4-Hydroxylases That Modify HIFScience, 2001
- C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl HydroxylationCell, 2001