Aromatic retinal analogs and their interaction with cattle opsin

Abstract

The preparation of 7 aromatic analogues of retinal, the isolation and characterization of their geometric isomers and the interaction of these isomers with cattle opsin are reported. Within certain limitations, it was demonstrated that stable aromatic rhodopsin analogues can be prepared. The stereoselectivity of isomers of these compounds in their interaction with opsin and the absorption properties of the resultant pigments are generally similar to those of the parent retinal.