Simple Method for the Esterification of Carboxylic Acids
- 1 July 1978
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 17 (7), 522-524
- https://doi.org/10.1002/anie.197805221
Abstract
Addition of 4‐dimethylaminopyridine (DMAP) accelerates the dicyclohexylcarbo‐diimide (DCC)‐activated esterification of carboxylic acids to such an extent that side reactions are eliminated and even sensitive acids such 2,5‐cyclohexadiene‐1‐carboxylic acid readily form the tert‐butyl ester. DMAP has so far been used mainly as acylation catalyst. equation imageKeywords
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