Skin typing for assessment of skin cancer risk and acute response to UV-B and oral methoxsalen photochemotherapy
- 1 July 1984
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 120 (7), 869-873
- https://doi.org/10.1001/archderm.120.7.869
Abstract
• Skin typing is a clinical classification system based on a patient's historical reporting of the acute skin response to sunlight. It is advocated as a means of determining an individual's relative risk of skin tumors and has been used to determine the initial therapeutic dose of UV radiation for UV-B phototherapy or oral methoxsalen photochemotherapy (PUVA) for psoriasis. Among PUVA-treated patients, the relative risk of cutaneous carcinoma was significantly higher among patients with skin types I and II compared with patients with skin type IV (3.2 and 2.3, respectively). Skin type was a better predictor of this risk than eye or hair color. The minimal erythemal dose (MErD) and minimal phototoxic dose (MPD) increased with increasing skin type number, but within a given skin type each varied as much as sixfold. Skin type was a good clinical predictor of skin cancer risk, but lacked specificity as a predictor of an individual's MErD or MPD. (Arch Dermatol1984;120:869-873)This publication has 3 references indexed in Scilit:
- Plasma Levels of 8-Methoxypsoralen Determined by High-Pressure Liquid Chromatography in Psoriatic Patients Ingesting Drug from Two ManufacturersJournal of Investigative Dermatology, 1980
- Risk of Cutaneous Carcinoma in Patients Treated with Oral Methoxsalen Photochemotherapy for PsoriasisNew England Journal of Medicine, 1979
- Sun and SkinDermatology, 1975