Cloning and characterization of the DNA of a new human papillomavirus from a woman with dysplasia of the uterine cervix
- 1 April 1986
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 58 (1), 225-229
- https://doi.org/10.1128/jvi.58.1.225-229.1986
Abstract
A previous analysis of 121 female genital tract lesions from the United States and South America had revealed that a large number contained DNA sequences that were weakly homologous to a panel of human papillomavirus (HPV) probes. The DNA sequences of one of these viruses have been molecularly cloned and shown to be a new ype of HPV which is called HPV 31. Among the cloned HPV genomes, HPV 31 is most closely related to HPV 16. Although absent from all genital condylomas studied, HPV 31 was present in approximately 20% of the mild and moderate dysplasias and in 6% of the invasive cervical cancers.This publication has 34 references indexed in Scilit:
- Human papillomavirus type 16 DNA sequenceVirology, 1985
- Biology and biochemistry of papillomavirusesReviews of physiology, biochemistry and pharmacology, 1984
- Identification of Human Papillomavirus DNA in Cervical and Vaginal Intraepithelial Neoplasia with Molecularly Cloned Virus-Specific DNA ProbesInternational Journal of Gynecological Pathology, 1983
- Detection of human papillomavirus DNA in anogenital neoplasiasNature, 1982
- Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNAInternational Journal of Cancer, 1982
- Molecular Cloning, Refined Physical Map and Heterogeneity of Methylation Sites of Papilloma Virus Type 1a DNAEuropean Journal of Biochemistry, 1980
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Screening λgt Recombinant Clones by Hybridization to Single Plaques in SituScience, 1977
- Detection of specific sequences among DNA fragments separated by gel electrophoresisJournal of Molecular Biology, 1975
- A membrane-filter technique for the detection of complementary DNABiochemical and Biophysical Research Communications, 1966