Two configurations of a channel-forming membrane protein
- 1 February 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 307 (5952), 609-613
- https://doi.org/10.1038/307609a0
Abstract
The protein oligomer forming the gap junction channel was analyzed in 2 Ca2+-sensitive states by EM of [rat liver] membranes in frozen aqueous solutions. Switching between states occurs by a small cooperative rearrangement involving tilting of the subunits, which may be responsible for the effect of Ca2+ on channel permeability in vivo.This publication has 23 references indexed in Scilit:
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