Studies on Scutellariae Radix. IV. Effect on lipid peroxidation in rat liver.

Abstract
Flavonoid components (wogonin, baicalein and baicalin) isolated from Scutellariae Radix ogon, [Root of Scutellaria-baicalensis] inhibited lipid peroxidation in intact rat liver stimulated by i.p. FeCl2-ascorbic acid-ADP mixture. Various flavonoids of ogon inhibited lipid peroxidation stimulated by FeCl2-ascorbic acid and NADPH-ADP mixture in rat liver homogenate. Baicalin, the major flavonoid component of ogon, reduced the increase of serum glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels in rats orally given an O2-bubbled rapeseed-corn-soybean oil mixture.