Pitting Function of the Spleen in Malaria: Ultrastructural Observations
- 14 July 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 177 (4044), 175-177
- https://doi.org/10.1126/science.177.4044.175
Abstract
Ultrastructural studies of spleens from monkeys infected with Plasmodium knowlesi suggest that the spleen removes or "pits" malaria parasites from red cells. This function may explain the presence of nonparasitized spherocytic erythrocytes in the peripheral blood and may in part account for the discrepancy between the excessive hemolysis and the number of parasitized erythrocytes in animals with experimentally induced malaria.Keywords
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