Dietary Bile Acids and Lipid Metabolism. I. Influence on Lipids and Liver Size of Chicks

Abstract

Summary Dietary lithocholic acid elevated plasma cholesterol and lipid phosphorus levels, and increased liver size of growing chicks. In cholesterol-fed chicks, lithocholic acid depressed liver lipid and cholesterol levels. The effects of lithocholic acid were partially reversed by cholic acid in chicks fed a cholesterol-free diet and almost completely reversed in chicks fed cholesterol. The plasma cholesterol level of cholesterol-fed chicks was increased by cholic acid feeding.