Synthesis of 1-Substituted 2-[(2S)-2-Pyrrolidinyl]pyridine from L-Proline

Abstract
The synthesis of optically active 2-[(2S)-2-pyrrolidinyl]pyridine from L-proline is reported. This compound can be further alkylated to give the corresponding N-methyl- and N-benzylpyrrolidinyl derivatives.