Epidemiology of primary biliary cirrhosis
- 1 June 1984
- journal article
- research article
- Published by Wiley in Liver International
- Vol. 4 (3), 195-200
- https://doi.org/10.1111/j.1600-0676.1984.tb00927.x
Abstract
A multi-national survey of the clinical and epidemiological aspects of primary biliary cirrhosis (PBC) was conducted in 10 countries in Western Europe, surveying a population of over 24 million. The prevalence on Dec. 31, 1981 was 23/million, but this showed a marked variation from center to center for reasons which are not clear. The annual incidence of PBC has remained constant at .apprx. 4/million over the past 4 yr, while the point prevalence has continued to rise, suggesting that the true prevalence may be rather higher than present figures suggest. The female:male sex ratio is 10:11, but in stages I and II this ratio is 6.5:1 compared with 11.4:1 in stages III and IV. Possible reasons for this are discussed.Keywords
This publication has 7 references indexed in Scilit:
- The Prognostic Importance of Clinical and Histologic Features in Asymptomatic and Symptomatic Primary Biliary CirrhosisNew England Journal of Medicine, 1983
- PRIMARY BILIARY CIRRHOSIS IN ELDERLY FEMALESAge and Ageing, 1982
- PRIMARY BILIARY CIRRHOSIS: EXPERIENCE IN A NON-REFERRAL CENTREThe Lancet, 1981
- Primary biliary cirrhosis: an epidemiological study.BMJ, 1980
- Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patientsGastroenterology, 1980
- Mitochondrial Antibody in Primary Biliary Cirrhosis and Other DiseasesAnnals of Internal Medicine, 1972