Favism: Association with Erythrocyte Acid Phosphatase Phenotype
- 29 January 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 171 (3969), 409-411
- https://doi.org/10.1126/science.171.3969.409
Abstract
The frequency of carriers of the Paand Pc alleles of the gene for acid phosphatase in the erythrocyte is significantly higher in male subjects deficient in glucose-6-phosphate dehydrogenase and having hemolytic clinical favism than it is in the general population. This observation seems to indicate that alleles (Pa and Pc) of a gene polymorphic in all human populations affect the fitness of the involved phenotypes in special genotypic and nongenotypic conditions.Keywords
This publication has 5 references indexed in Scilit:
- Studies on Genetically Different Acid Phosphatase of Human Red Cells*The Journal of Biochemistry, 1968
- Effect of oxidized glutathione on human red cell acid phosphatasesBiochemical and Biophysical Research Communications, 1964
- Quantitative Differences and Gene Dosage in the Human Red Cell Acid Phosphatase PolymorphismNature, 1964
- Red Cell Acid Phosphatase Variants: A New Human PolymorphismNature, 1963
- OXIDATIVE HEMOLYSIS AND PRECIPITATION OF HEMOGLOBIN. I. HEINZ BODY ANEMIAS AS AN ACCELERATION OF RED CELL AGING *Journal of Clinical Investigation, 1960