Abstract
Constitutional reactions, which rather frequently follow the administration of pollen extract, may be severe and even dangerous unless immediately controlled by experienced physicians. They occur with every method of pollen therapy with which I am acquainted. They can be reduced in likelihood of occurrence and in severity by careful adjustment of dosage and the time interval between injections and by avoidance of physical effort and exposure to heat after injections. However, in spite of all care, reactions rather frequently occur which may be so severe that many physicians and many patients have been induced to condemn pollen therapy as unjustifiable for the average patient with pollen hay-fever or asthma. Following several severe and apparently unavoidable reactions last year, I was tempted to discontinue pollen therapy unless I could devise a method which could be considered almost reaction proof. In this paper I shall describe a method which reduces the likelihood