Obstructive Sleep Apnea and Near Miss for SIDS: I. Report of an Infant With Sudden Death

Abstract

An infant girl followed-up from birth to death had congenital stridor and a near miss for SDIS [sudden infant death syndrome] event at 3 mo. of age. As part of an ongoing SIDS research project, she underwent 24 h polygraphic monitoring at 21 wk of age. SIDS occurred within 30 h after the polygraphic study. Polygraphic data obtained from this infant were compared with those from control infants and other infants with near miss for SIDS who were of similar ages. The number of mixed and obstructive respiratory events during sleep was abnormally high on the infant''s recording. Histologic findings, involving particularly the midline structures of the brainstem, were discussed.