The influence of previous diet on the fasting blood-sugar level and on glucose utilization in the rat and hamster
- 1 February 1955
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 59 (2), 224-228
- https://doi.org/10.1042/bj0590224
Abstract
After 17 hours fasting, blood-sugar levels from rats and hamsters fed on a high-fat diet from weaning are consistently lower than those from similar animals on a high-carbohydrate diet. The reduced tolerance to intravenously injected glucose induced by a high-fat diet was confirmed using rats. Restriction of carbohydrate intake by feeding excess fat or protein depresses both glucose uptake and glycogen synthesis by the isolated rat diaphragm. Hexokinase activity of kidney homogenates from rats and hamsters is depressed by high-fat diets.Keywords
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