The Respiration of Streptococcus pyogenes and Pneumococcus Type I

Abstract

The "anti-catalase" theory is untenable. These findings support the theory of Fildes to the extent that sulfanilamide interferes with or blocks a bacterial enzyme system; but sulfanilamide blocks primarily the respiratory enzymes, which in turn inhibit growth, rather than interfering with the synthetic processes necessary for growth as stated by Fildes.