Selenium status of a rural (predominantly Amish) community living in a low-selenium area

Abstract

Selenium intake and blood selenium and selenium-dependent glutathione peroxidase concentrations were assessed in a rural, 71% Amish, sample of residents in a region with low availability of soil selenium and in urban (Columbus, OH) residents. Subjects were interviewed (24-h dietary recalls) on three separate occasions over an 18-month period, and blood and food samples were taken for analysis (maximum subject observations = 452). Mean selenium intake of the entire population was 82.8 ± 4.4 μg/day. Rural and urban residents at 82.0 ± 4.9 and 83.6 ± 4.4 μg/day, respectively, did not differ significantly in intake. A breakdown by gender within location demonstrated that rural males consumed the most selenium (104.7 ± 6.1 Mg/day) and rural females the least (59.3 ± 6.3 μg/day). Rural subject groups had significantly lower mean whole blood, plasma, and erythrocyte selenium levels (12.5 to 14.5%) as well as blood selenium-dependent glutathione peroxidase concentrations (5.6 to 10.8%) than urban groups. Subjects in both cohorts were in adequate selenium status as judged by blood parameters, even though about one-fourth of the dietary observations were below the safe and adequate range of selenium intake established by the Food and Nutrition Board. The rural diet was 18.3% lower in selenium density than the urban diet. High selenium grain products (>0.2 μg/g) were the most important dietary selenium source in both groups, providing 29.3 to 41.6% of total intake.