PIANA: protein interactions and network analysis

Abstract

Summary: We present a software framework and tool called Protein Interactions And Network Analysis (PIANA) that facilitates working with protein interaction networks by (1) integrating data from multiple sources, (2) providing a library that handles graph-related tasks and (3) automating the analysis of protein–protein interaction networks. PIANA can also be used as a stand-alone application to create protein interaction networks and perform tasks such as predicting protein interactions and helping to identify spots in a 2D electrophoresis gel. Availability: PIANA is under the GNU GPL. Source code, database and detailed documentation may be freely downloaded from . Contact: ramon.aragues@upf.edu; boliva@imim.es