The Loss of Fluid and Protein From the Blood During a Systemic Rise of Venous Pressure Produced by Repeated Valsalva Maneuvers in Man1
Open Access
- 1 November 1958
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 37 (11), 1465-1475
- https://doi.org/10.1172/jci103738
Abstract
In healthy subjects, the effect of sustained elevation of venous pressure, 11-21 cm H2O above normal, (accomplished by repeated Valsalva maneuvers, made in a manner similar to that observed during obstetric labor) on blood volume was studied, by means of changes in venous hematocrit, plasma protein and T-1824 concentrations. The initial loss of fluid is rapid amounting to 3 to 10% of blood volume, but falls off rapidly as a new equilibrium is reached between intra and extravascular compartments. The rate of filtration is similar to that observed during localized congestion of the forearm.This publication has 26 references indexed in Scilit:
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