Direct Chain Elongation of N-Carbamoylpyroglutamate. An Efficient Synthesis of (−)-Pyrrolidine-2,5-Dicarboxylic Acid
- 5 October 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 16 (10), 2091-2094
- https://doi.org/10.1246/cl.1987.2091
Abstract
(−)-Pyrrolidine-2,5-dicarboxylic acid, an acidic amino acid component of marine red alga Schizymenia dubyi, has been synthesized with a direct chain elongation reaction of N-carbamoylpyroglutamates at C-5 and a pyrrolidine ring formation.Keywords
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