A method for the quantitative determination in urinary extracts of C21 17:20-dihydroxy-20-methylsteroids
- 1 October 1952
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 52 (2), 339-345
- https://doi.org/10.1042/bj0520339
Abstract
The method is based on periodic acid oxidation. It allows simultaneous estimation of acetaldehydogenic and formalde-hydogenic steroids. A urinary excretion of unconjugated acetaldehydogenic material equivalent to 0.1-0.5 mg./day of C21 17, 20 -dihydroxy-20-methylsteroids was found for 7 normal males. The presence of conjugated acetaldehydogenic material in normal male urine is also indicated.Keywords
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