The origin of experimental brain tumours: A sequential study
- 1 November 1976
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 32 (11), 1467-1468
- https://doi.org/10.1007/bf01937439
Abstract
Summary A sequential study of rat brains treated transplacentally with the neurotropic carcinogen ethylnitrosourea reveals small foci of cell proliferations from the age of 8 weeks. These lesions consist mainly of undifferentiated cells of the subependymal plate type. They occur in those areas in which gliomas develop and represent the earliest, histologically detectable, changes in the development of brain tumours.Keywords
This publication has 13 references indexed in Scilit:
- Chemical carcinogenesis in the nervous system.1976
- Tumours of the nervous system induced in rats by the neonatal administration of n‐ethyl‐n‐nitrosoureaThe Journal of Pathology, 1973
- The fine structure of periventricular pleomorphic gliomas induced transplacentally by N-ethyl-N-nitrosourea in BD-IX Rats: With a note on their originJournal of the Neurological Sciences, 1972
- Toxicity of nitrosamines: Their possible human health hazardsFood and Cosmetics Toxicology, 1971
- PATHOLOGY OF EXPERIMENTAL NEUROGENIC TUMORS CHEMICALLY INDUCED DURING PRENATAL AND POSTNATAL LIFEAnnals of the New York Academy of Sciences, 1969
- The ultrastructure of the subependymal plate in the rat.1969
- Transplacentare Erzeugung maligner Tumoren des NervensystemsZeitschrift für Krebsforschung und Klinische Onkologie, 1968
- [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].1967
- Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-RattenZeitschrift für Krebsforschung und Klinische Onkologie, 1967
- Teratogenic and Carcinogenic Effects in the Offspring after Single Injection of Ethylnitrosourea to Pregnant RatsNature, 1966