Meta-Analyses of the Relation between Silicone Breast Implants and the Risk of Connective-Tissue Diseases
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- 16 March 2000
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 342 (11), 781-790
- https://doi.org/10.1056/nejm200003163421105
Abstract
The postulated relation between silicone breast implants and the risk of connective-tissue and autoimmune diseases has generated intense medical and legal interest during the past decade. The salience of the issue persists, despite the fact that a great deal of research has been conducted on this subject. To provide a stronger quantitative basis for addressing the postulated relation, we applied several techniques of meta-analysis that combine, compare, and summarize the results of existing relevant studies.Keywords
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