The purpose of this study was to investigate whether remineralization of artificial caries-like lesions by artificial saliva could be improved by daily 5-min ‘dips’ in a specially formulated ‘dipping’ solution. The dipping solution contained Ca, PO4, Zn, Sr and F. Remineralization versus remineralization/dipping was studied on MHDP/lactate lesions produced in adjacent halves of human premolars and was assessed using microradiography and microhardness. Both techniques were consistent in showing a considerable remineralization by artificial saliva and an additive effect by the dipping solution. This effect was most pronounced in the lesion body and inner zone, where the amount of mineral deposited was approximately doubled. The use of the dipping solution also increased the hardness of the sound enamel beyond the inner zone. Microhardness and microradiography correlation data on individual samples were in agreement with the previously established relationship between the two techniques.