Hypothesis: when is a seminoma not a seminoma?
Open Access
- 1 February 1981
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 34 (2), 123-128
- https://doi.org/10.1136/jcp.34.2.123
Abstract
A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, and ultrastructural studies of this xenograft line have suggested that a solid variant of yolk sac carcinoma may exist, which morphologically resembles seminoma, or that a continuum of differentiation exists between seminoma and yolk sac carcinoma.This publication has 9 references indexed in Scilit:
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