THE CELLULAR TRANSFORMATION OF INJECTED COLLOIDAL IRON COMPLEXES INTO FERRITIN AND HEMOSIDERIN IN EXPERIMENTAL ANIMALS
Open Access
- 1 February 1959
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 109 (2), 197-216
- https://doi.org/10.1084/jem.109.2.197
Abstract
As revealed by electron microscopy and electron diffraction, the physical state of ferric hydroxide micelles contained in iron-dextran, saccharated iron oxide, and hydrous ferric oxide ("ferric hydroxide") differs notably from the state of the ferric hydroxide in ferritin or hemosiderin. By virtue of this difference one can trace the intracellular transformation of colloidal iron, administered parenterally, into ferritin and hemosiderin.Keywords
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