Distributive Pairing and Aneuploidy in Man
- 3 July 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3627), 66-67
- https://doi.org/10.1126/science.145.3627.66
Abstract
The extrapolation of the "distributive-pairing hypothesis" of meiosis in Drosophila melanogaster females to human gametogenesis is proposed to account for the co-occurrence of rare karyotype abnormalities in human families. A description of the hypothesis is presented with its application to some established cases in the cytogenetic literature.Keywords
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