Heavy Metal Nephropathy of Rodents
Open Access
- 1 August 1978
- journal article
- research article
- Published by SAGE Publications in Veterinary Pathology
- Vol. 15 (5_suppl), 51-87
- https://doi.org/10.1177/0300985878015s0507
Abstract
Heavy metal nephropathy is a pathologic entity of the renal tubular epithelium of rats, evoked by lead, gold, and other heavy metals. It is characterized acutely by coagulative necrosis, subacutely by cortical fibrosis, and chronically by cytomegaly and karyomegaly. Finally, adenomas develop, some of which become malignant.Keywords
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