Huntington's Chorea—Some Biochemical and Therapeutic Aspects

Abstract

Huntington's Chorea presents us with a good “model” of brain disease in that we know the extent of the contribution of heredity, in contrast to a condition such as schizophrenia regarding which many authors (cf. Alanen, 1958) would be prepared to defend the concept of pseudo-heredity. Secondly the disease carries a fairly uniform prognosis, and finally it results in a distinctive disturbance of motor function which permits of some accuracy in diagnosis and some criterion for objective measurement.