Prognostic value of breast cancer aromatase
- 1 October 1992
- Vol. 70 (7), 1951-1955
- https://doi.org/10.1002/1097-0142(19921001)70:7<1951::aid-cncr2820700723>3.0.co;2-#
Abstract
The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease-free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease-free interval or survival.Keywords
This publication has 13 references indexed in Scilit:
- Aromatase activity in primary and metastatic human breast cancerCancer, 1987
- Biological Significance of Aromatase Activity in Human Breast Tumors*Journal of Clinical Endocrinology & Metabolism, 1983
- Maternal Stress Decreases Steroid Aromatase Activity in Brains of Male and Female Rat FetusesNeuroendocrinology, 1982
- The conversion of androstenedione to estrone, estradiol, and testosterone in breast tissueJournal of Steroid Biochemistry, 1980
- Identification of the estrogen product of extraglandular aromatization of plasma androstenedioneAmerican Journal of Obstetrics and Gynecology, 1978
- Steroid metabolism by human mammary carcinomaSteroids, 1976
- Oestradiol synthesis from C19 steroids by human breast cancersBritish Journal of Cancer, 1976
- Androgen Production and Conversion to Estrogens in Normal Postmenopausal Women and in Selected Breast Cancer PatientsJournal of Clinical Endocrinology & Metabolism, 1973
- Source of Estrogen Production in Postmenopausal Women1Journal of Clinical Endocrinology & Metabolism, 1973
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958