Aspects cliniques et hématologiques de la réticulose maligne

Abstract

A clinical report and review of the literature which characterizes this disease as an invasive, irreversible, atypical and systematic proliferation of reticulohistiocytic cells. According to the different localizations it is possible to distinguish 3 large clinical groups: visceral or pseudo-leukemic forms, chiefly involving the liver, spleen and lymph nodes, dermatologic forms, chiefly involving the skin, and an early childhood form, also known under the name of Abt-Letterer-Siwe''s disease. The malignant reticuloses must be differentiated from the monocytic leukemias of the Naegeli or Marchal type, from malignant lymphogranulomatosis, from mycosis fungoides, from eosinophilic granuloma, xantho-matoses and reticulosarcomas.